Zach Galifianakis
Some of you may be more familiar with him from his work on Between Two Ferns, while others may recognize him from the Hangover trilogy. In any case, Zach Galifianakis is remembered as a big guy by a lot of people. After quitting drinking in 2014, he lost an incredible 50 pounds, which he credits to his newfound discipline.
Jonah Hill
Jonah Hill is absolutely deserving of all of the praise he has been receiving for his weight loss efforts. If you are familiar with him from the Superbad series, it is possible that you will not recognize him now.